Anteroventral third ventricle lesions abolish lumbar sympathetic responses to insulin.
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چکیده
منابع مشابه
Anteroventral third ventricle lesions abolish lumbar sympathetic responses to insulin.
Insulin has been shown to increase sympathetic nerve activity. Because evidence shows that insulin acts within the central nervous system, we hypothesized that lesions of the anteroventral third ventricle region, an area rich in insulin receptors, would abolish sympathetic responses to hyperinsulinemia. We measured mean arterial pressure and lumbar sympathetic nerve activity in fasted, anesthet...
متن کاملLesions of the anteroventral third ventricle region (AV3V) disrupt cardiovascular responses to an elevation in core temperature.
Blood flow is redistributed from the viscera to the periphery during periods of heat stress to maximize heat loss. The heat-induced redistribution of blood flow is strongly influenced by nonthermal inputs such as hydration status. At present, little is known about where thermal and nonthermal information is integrated to generate an appropriate effector response. Recently, the periventricular t...
متن کاملLesions of the anteroventral third ventricle region exaggerate neuroendocrine and thermogenic but not behavioral responses to a novel environment.
Mild psychological stressors provoke an acute rise in core temperature (T(C)), stimulate the hypothalamo-pituitary-adrenocortical (HPA) axis, and induce various stress-related behaviors. In the present study, we examined the effect of ablation of the anteroventral third ventricle region (AV3V) on both physiological and behavioral responses to a novel environment. T(C) was monitored in male Spra...
متن کاملLesions of the anteroventral third ventricle prevent salt-induced hypertension in the borderline hypertensive rat.
Many forms of experimental hypertension depend on the integrity of the periventricular tissue surrounding the anteroventral third ventricle. The current investigation examined the extent to which this forebrain area is necessary for the elaboration of salt-induced hypertension in the borderline hypertensive rat. Eight-week-old male rats were given either electrolytic lesions of the anteroventra...
متن کاملEffect of anteroventral third ventricle lesions on vascular sodium-pump activity in two-kidney Goldblatt hypertension.
We studied the effects of anteroventral third ventricle (AV3V) lesions on the vascular Na+-pump activity and blood pressure of rats prepared by the two-kidney Goldblatt procedure. Blood pressures and Na+-pump activity of the isolated tail arteries, measured as ouabain-sensitive 86Rb+-uptake were determined in rats with renal artery clips, rats with AV3V lesions, and rats with AV3V lesions. Rats...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1994
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.23.6.1059